Long-term psychological effects of a no-sedation protocol in critically ill patients

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Long-term psychological effects of a no-sedation protocol in critically ill patients

INTRODUCTION A protocol of no sedation has been shown to reduce the time patients receive mechanical ventilation and to reduce intensive care and total hospital length of stay. The long-term psychological effects of this strategy have not yet been described. The purpose of the study was to test whether a strategy of no sedation alters long-term psychological outcome compared with a standard str...

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A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.

BACKGROUND Standard treatment of critically ill patients undergoing mechanical ventilation is continuous sedation. Daily interruption of sedation has a beneficial effect, and in the general intesive care unit of Odense University Hospital, Denmark, standard practice is a protocol of no sedation. We aimed to establish whether duration of mechanical ventilation could be reduced with a protocol of...

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Sedation in critically ill patients.

Sedation in the intensive care unit (ICU) is a topic that has been frequently researched, and debate still exists as to what are the best sedative agents for critically ill patients. There is increasing interest in sleep and circadian rhythm disturbances in the ICU and how they may impact on outcomes. In addition to patient-related and ICU environmental factors that likely impact sleep and circ...

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Alpha-2 agonists for long-term sedation during mechanical ventilation in critically ill patients.

BACKGROUND Sedation reduces patient levels of anxiety and stress, facilitates the delivery of care and ensures safety. Alpha-2 agonists have a range of effects including sedation, analgesia and antianxiety. They sedate, but allow staff to interact with patients and do not suppress respiration. They are attractive alternatives for long-term sedation during mechanical ventilation in critically il...

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Early intensive care sedation predicts long-term mortality in ventilated critically ill patients.

RATIONALE Choice and intensity of early (first 48 h) sedation may affect short- and long-term outcome. OBJECTIVES To investigate the relationships between early sedation and time to extubation, delirium, and hospital and 180-day mortality among ventilated critically ill patients in the intensive care unit (ICU). METHODS Multicenter (25 Australia and New Zealand hospitals) prospective longit...

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ژورنال

عنوان ژورنال: Critical Care

سال: 2011

ISSN: 1364-8535

DOI: 10.1186/cc10586